Protein Alignment CG7142 and PRSS22

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 83/310 - (26%)
• Similarity: 142/310 - (45%)
• Gaps: 32/310 - (10%)

  Fly    34 PTVRKCGGGRSAGA-------AHTMAMNLAAYGLLE-NRISTLEAPRQTHWTKKFLAKREATPHS 90
            |..|||..||..|.       .|..|...:...:|. .||....|..:.....:.:...::|...
Human   104 PGPRKCPAGRGPGVERLESLPGHWRARGSSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE 168

  Fly    91 APYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC----LSSPQAVENSVIVAGSHDIHDQKGE 151
            .|::||||     :...|:|||:::...|::|||||    |:.|....   ::.|:..:.:....
Human   169 WPWIVSIQ-----KNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFS---VLLGAWQLGNPGSR 225

  Fly   152 ASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQ--PEGYGTLYGW 214
            :..:.:..::.:..:....|..  .||||:..:..:.|...|.|..||:....  |..:..:.||
Human   226 SQKVGVAWVEPHPVYSWKEGAC--ADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW 288

  Fly   215 GNVSMTAVPNYPHRLQEANMPILDMELCEQILARSG--LPLHETNLCTGPLTGGVSICTADSGGP 277
            |::.......:|..||:..:||:|.|:|..:..|..  .|:.|..||.|.|.|....|..|||||
Human   289 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGP 353

  Fly   278 LIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVI 327
            |:.|     .:.|.::.||:|||: .|.::|.|.|::.:||...|:.:::
Human   354 LMCQ-----VDGAWLLAGIISWGE-GCAERNRPGVYISLSAHRSWVEKIV 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	70/249 (28%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	70/253 (28%)