DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and TMPRSS4

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:XP_005271670.1 Gene:TMPRSS4 / 56649 HGNCID:11878 Length:494 Species:Homo sapiens


Alignment Length:257 Identity:85/257 - (33%)
Similarity:124/257 - (48%) Gaps:33/257 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 TKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAG 141
            |.:.:...||:..|.|:.||||.   |:  .|.|.|:|::.||:||||||......|.|..:.||
Human   202 TPRVVGVEEASVDSWPWQVSIQY---DK--QHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAG 261

  Fly   142 SHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLP--EQDAQ 204
            |    |:.|...::.:..|.....:.:|   ....||||:..:.||.|...|:|..||  :::..
Human   262 S----DKLGSFPSLAVAKIIIIEFNPMY---PKDNDIALMKLQFPLTFSGTVRPICLPFFDEELT 319

  Fly   205 PEGYGTLYGWG-----NVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLT 264
            |.....:.|||     ...|:.:      |.:|::.::|...|....|..| .:.|..:|.|...
Human   320 PATPLWIIGWGFTKQNGGKMSDI------LLQASVQVIDSTRCNADDAYQG-EVTEKMMCAGIPE 377

  Fly   265 GGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQV 326
            |||..|..||||||:.|..:.|      |:|||||| ..||..:.|.|:.:|||:..||..|
Human   378 GGVDTCQGDSGGPLMYQSDQWH------VVGIVSWG-YGCGGPSTPGVYTKVSAYLNWIYNV 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 83/248 (33%)
TMPRSS4XP_005271670.1 LDLa 58..92 CDD:238060
SRCR_2 108..197 CDD:470597
Tryp_SPc 204..429 CDD:214473 81/250 (32%)
Blue background indicates that the domain is not in the aligned region.

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