Protein Alignment CG7142 and PRSS2

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 84/280 - (30%)
• Similarity: 122/280 - (43%)
• Gaps: 61/280 - (21%)

  Fly    80 FLAKREATP---------------HSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSS 129
            |:|...|.|               :|.||.||:     :.| .|:|.|::|:|.|:::|.||..|
Human     9 FVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-----NSG-YHFCGGSLISEQWVVSAGHCYKS 67

  Fly   130 PQAVENSV-----------IVAGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYT 183
              |:.:.:           :..|.|:|...:|....|....|   :||..|.......||.||..
Human    68 --AINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKI---IRHPKYNSRTLDNDILLIKL 127

  Fly   184 KEPLVFDTYVQPATLPEQDAQPEGYGT---LYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQI 245
            ..|.|.::.|...:||   ..|...||   :.|||| ::::..:||..||..:.|:|....||
Human   128 SSPAVINSRVSAISLP---TAPPAAGTESLISGWGN-TLSSGADYPDELQCLDAPVLSQAECE-- 186

  Fly   246 LARSGLPLHETN--LCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKN 308
               :..|...||  .|.|.|.||...|..|||||::..         ..:.|||||| ..|.|||
Human   187 ---ASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSN---------GELQGIVSWG-YGCAQKN 238

  Fly   309 APSVFVRVSAFTEWINQVIS 328
            .|.|:.:|..:.:||...|:
Human   239 RPGVYTKVYNYVDWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	81/272 (30%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	79/261 (30%)