Protein Alignment CG7142 and PLAT

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 81/314 - (25%)
• Similarity: 128/314 - (40%)
• Gaps: 73/314 - (23%)

  Fly    33 LPTVRKCGGGRSAGAAHTMAMNLAAYGLLENRI-STLEAPRQTH-WTKKFLAKREATPHSAPYVV 95
            :|:...||              |..|...:.|| ..|.|...:| |.....||...:|
Human   293 VPSCSTCG--------------LRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSP------- 336

  Fly    96 SIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSS---PQAVENSVIVAGSHDI----HDQKGEAS 153
                     |....|.|.:|:..|||:||||...   |..:  :||:..::.:    .:||.|
Human   337 ---------GERFLCGGILISSCWILSAAHCFQERFPPHHL--TVILGRTYRVVPGEEEQKFE-- 388

  Fly   154 NIQMRHIDYYVRHELYLGGVNPYDIALIYTKEP----LVFDTYVQPATLPEQDAQPEGYG--TLY 212
                  ::.|:.|:.:.......||||:..|..    ....:.|:...||..|.|...:.  .|.
Human   389 ------VEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELS 447

  Fly   213 GWGNVSMTAVPNYPHRLQEANMPILDMELC--EQILARSGLPLHETNLCTGPLTGG------VSI 269
            |:|.....: |.|..||:||::.:.....|  :.:|.|:   :.:..||.|....|      ...
Human   448 GYGKHEALS-PFYSERLKEAHVRLYPSSRCTSQHLLNRT---VTDNMLCAGDTRSGGPQANLHDA 508

  Fly   270 CTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
            |..||||||:  |..   :....::||:||| :.||||:.|.|:.:|:.:.:||
Human   509 CQGDSGGPLV--CLN---DGRMTLVGIISWG-LGCGQKDVPGVYTKVTNYLDWI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	68/261 (26%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005	1/2 (50%)
		Tryp_SPc	313..559	CDD:238113	74/280 (26%)