Protein Alignment CG7142 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 323
• Identity: 88/323 - (27%)
• Similarity: 133/323 - (41%)
• Gaps: 72/323 - (22%)

  Fly    25 SASSGSIQLPTVRKCGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPRQTHWTKKFLAKREATPH 89
            :.|||::.|  .:|.....|..:...:::.....|:           |......:.:....|:|.
Mouse   212 NVSSGNVDL--YKKLYHSDSCSSRMVVSLRCIECGV-----------RSVKRQSRIVGGLNASPG 263

  Fly    90 SAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC----LSSPQ-------AVENSVIVAGSH 143
            ..|:.||:.:    || ||.|.|:||...||:|||||    ||||:       .:..|::..||
Mouse   264 DWPWQVSLHV----QG-VHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGS- 322

  Fly   144 DIHDQKGEASNIQMRH-IDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLP-------- 199
                          || ::..:.|..|.......||||:..:.||.|:..|:|..||
Mouse   323 --------------RHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDL 373

  Fly   200 EQDAQPEGYGTLYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLT 264
            :|:....|:|..|..|..|..        |..|.:|:::...|......:.| :....:|.|.|.
Mouse   374 DQECWISGWGATYEKGKTSDV--------LNAAMVPLIEPSKCNSKYIYNNL-ITPAMICAGFLQ 429

  Fly   265 GGVSICTADSGGPLIQQCCEEHFEQANI--VIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQ 325
            |.|..|..||||||:..       :..|  :||..|||. .|.:...|.|:..|:.||:||.|
Mouse   430 GSVDSCQGDSGGPLVTL-------KNGIWWLIGDTSWGS-GCAKALRPGVYGNVTVFTDWIYQ 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	80/264 (30%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:464747	7/47 (15%)
		Tryp_SPc	254..485	CDD:238113	80/268 (30%)