DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and LPA

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_005568.2 Gene:LPA / 4018 HGNCID:6667 Length:2040 Species:Homo sapiens


Alignment Length:248 Identity:81/248 - (32%)
Similarity:112/248 - (45%) Gaps:50/248 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 ATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSH-----DI 145
            |.|||.|:.||::.....    |:|.||:|:..|:|||||||.......:..::.|:|     :.
Human  1826 AHPHSWPWQVSLRTRFGK----HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLES 1886

  Fly   146 HDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQD----AQPE 206
            |.|:.|.|             .|:|..... ||||:....|.|....|.||.||..|    |:.|
Human  1887 HVQEIEVS-------------RLFLEPTQA-DIALLKLSRPAVITDKVMPACLPSPDYMVTARTE 1937

  Fly   207 GYGTLYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICT 271
            .|.|  |||....|.....   |:||.:.:::.|:|.          |...:|...|..|...|.
Human  1938 CYIT--GWGETQGTFGTGL---LKEAQLLVIENEVCN----------HYKYICAEHLARGTDSCQ 1987

  Fly   272 ADSGGPLIQQCCEEHFEQANIVI-GIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
            .||||||:   |   ||:...:: |:.||| :.|.:.|.|.|:.|||.|..||
Human  1988 GDSGGPLV---C---FEKDKYILQGVTSWG-LGCARPNKPGVYARVSRFVTWI 2033

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 81/248 (33%)
LPANP_005568.2 Kringle 28..105 CDD:395005
Kringle 142..219 CDD:395005
Kringle 256..333 CDD:395005
Kringle 370..447 CDD:395005
Kringle 484..561 CDD:395005
Kringle 598..675 CDD:395005
Kringle 712..789 CDD:395005
Kringle 826..903 CDD:395005
KR 938..1019 CDD:214527
Kringle 1054..1131 CDD:395005
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1147..1166
KR 1166..1246 CDD:214527
KR 1272..1352 CDD:214527
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1365..1388
KR 1386..1466 CDD:214527
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1476..1497
KR 1500..1581 CDD:214527
KR 1614..1695 CDD:214527
Kringle 1720..1799 CDD:395005
Tryp_SPc 1820..2034 CDD:238113 81/248 (33%)
Blue background indicates that the domain is not in the aligned region.

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