Protein Alignment CG7142 and KLKB1

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 68/239 - (28%)
• Similarity: 114/239 - (47%)
• Gaps: 27/239 - (11%)

  Fly    92 PYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQKGEASNIQ 156
            |:.||:|:....|.  |.|.|::|...|:||||||.......:...|.:|..::.|...:....|
Human   414 PWQVSLQVKLTAQR--HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQ 476

  Fly   157 MRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQPEGYGTLY------GWG 215
            ::.|   :.|:.|......:|||||..:.||.:..:.:|..||.:.    ...|:|      |||
Human   477 IKEI---IIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG----DTSTIYTNCWVTGWG 534

  Fly   216 -NVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICTADSGGPLI 279
             :.....:.|.   ||:.|:|::..|.|::  ......:.:..:|.|...||...|..||||||:
Human   535 FSKEKGEIQNI---LQKVNIPLVTNEECQK--RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLV 594

  Fly   280 QQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
               |:.:....  ::||.|||: .|.::..|.|:.:|:.:.:||
Human   595 ---CKHNGMWR--LVGITSWGE-GCARREQPGVYTKVAEYMDWI 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	68/239 (28%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519
		Tryp_SPc	402..632	CDD:238113	66/237 (28%)