Protein Alignment CG7142 and KLK2

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 81/326 - (24%)
• Similarity: 127/326 - (38%)
• Gaps: 89/326 - (27%)

  Fly    19 IMVVLSSASSGSIQLPTVRKCGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPRQTHWTKKFLAK 83
            :.:.||...:|::.|...|..||                                  |
Human     6 LSIALSVGCTGAVPLIQSRIVGG----------------------------------W------- 29

  Fly    84 REATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQ 148
             |...||.|:.|::.    ..|..| |.|.:::..|:|||||||.     :||.:..|.|::.:.
Human    30 -ECEKHSQPWQVAVY----SHGWAH-CGGVLVHPQWVLTAAHCLK-----KNSQVWLGRHNLFEP 83

  Fly   149 KGEASNIQMRHIDYYVRHELYLGGV-----------NPYDIALIYTKEPLVFDTYVQPATLPEQD 202
            :.....:.:.|   ...|.||...:           :.:|:.|:...||......|:...||.|
Human    84 EDTGQRVPVSH---SFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ- 144

  Fly   203 AQPEGYGTLY--GWGNVSMTAVPN---YPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGP 262
             :|....|.|  |||::.    |.   .|..||..::.:|..::|.:..:..   :.|..||.|.
Human   145 -EPALGTTCYASGWGSIE----PEEFLRPRSLQCVSLHLLSNDMCARAYSEK---VTEFMLCAGL 201

  Fly   263 LTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVI 327
            .|||...|..||||||:   |.      .::.||.|||..||.....|:|:.:|..:.:||...|
Human   202 WTGGKDTCGGDSGGPLV---CN------GVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

  Fly   328 S 328
            :
Human   258 A 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	72/257 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	75/303 (25%)