Protein Alignment CG7142 and KLK1

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 75/265 - (28%)
• Similarity: 119/265 - (44%)
• Gaps: 56/265 - (21%)

  Fly    85 EATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQK 149
            |...||.|:..::...:..|     |.|.:::..|:||||||:|     :|..:..|.|::.|.:
Human    30 ECEQHSQPWQAALYHFSTFQ-----CGGILVHRQWVLTAAHCIS-----DNYQLWLGRHNLFDDE 84

  Fly   150 GEASNIQMRHIDYYVRHELYLGGVN---------------PYDIALIYTKEPLVFDTY---VQPA 196
            ..|   |..|:.....|.    |.|               .:|:.|:...||.  ||.   |:..
Human    85 NTA---QFVHVSESFPHP----GFNMSLLENHTRQADEDYSHDLMLLRLTEPA--DTITDAVKVV 140

  Fly   197 TLPEQDAQPEGYGTLYGWGNVSMTAVP---NYPHRLQEANMPILDMELCEQILARSGLPLHETNL 258
            .||.::.:........|||::.    |   ::|..||..::.||..:.|::...:.   :.:..|
Human   141 ELPTEEPEVGSTCLASGWGSIE----PENFSFPDDLQCVDLKILPNDECKKAHVQK---VTDFML 198

  Fly   259 CTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
            |.|.|.||...|..||||||:   |:      .::.|:.|||.:|||..|.|||.|||.::.:||
Human   199 CVGHLEGGKDTCVGDSGGPLM---CD------GVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWI 254

  Fly   324 NQVIS 328
            ...|:
Human   255 EDTIA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	74/261 (28%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	74/261 (28%)