Protein Alignment CG7142 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 93/325 - (28%)
• Similarity: 146/325 - (44%)
• Gaps: 55/325 - (16%)

  Fly    10 SVLLSTIASIMVVLSSASSGSIQLPTVRKCGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPRQT 74
            |.::||....|..||:.....:.:|.:::| |.|.|                      :|.|
Human   497 SPVVSTPTKSMQALSTVPLDWVTVPKLQEC-GARPA----------------------MEKP--- 535

  Fly    75 HWTKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIV 139
               .:.:....|.....|:.||::     :|..|:|..|::.:.|:|:||||.:..: ||.....
Human   536 ---TRVVGGFGAASGEVPWQVSLK-----EGSRHFCGATVVGDRWLLSAAHCFNHTK-VEQVRAH 591

  Fly   140 AGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQ 204
            .|:..:....|....|.:|.:   |.|.||..|:..:|:|::....||.|:.|:||..||....:
Human   592 LGTASLLGLGGSPVKIGLRRV---VLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQK 653

  Fly   205 -PEGYGTLY-GWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGV 267
             |.|...:. |||| :.......|..||:|::.|:|.:.|..:.   ...|.:..:|.|.|.|.|
Human   654 FPVGRKCMISGWGN-TQEGNATKPELLQKASVGIIDQKTCSVLY---NFSLTDRMICAGFLEGKV 714

  Fly   268 SICTADSGGPLIQQCCEEH---FEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVIST 329
            ..|..||||||   .|||.   |..|    |||||| :.|.|...|.|:.|::....||.:::|:
Human   715 DSCQGDSGGPL---ACEEAPGVFYLA----GIVSWG-IGCAQVKKPGVYTRITRLKGWILEIMSS 771

  Fly   330  329
            Human   772  771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	79/246 (32%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113	79/250 (32%)
		Pneumo_att_G	<717..>867	CDD:114270	26/63 (41%)
		Tryp_SPc	861..1087	CDD:238113