DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7142 and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_650703.1	Gene:	CG7142 / 42194	FlyBaseID:	FBgn0038595	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	314	Identity:	82/314 - (26%)
Similarity:	118/314 - (37%)	Gaps:	93/314 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 CGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPRQTHWTKKFLAKREATPHSAPYVVSIQMMTPD 103
            |...||:.|.|.:.          ....|||.    .|               |:.||:..:..
Human   594 CTCSRSSSALHRII----------GGTDTLEG----GW---------------PWQVSLHFVGS- 628

  Fly   104 QGLVHYCAGTIINEHWILTAAHCL-------SSPQAVENSVIVAGSHDIHDQKGEASNIQ-MRHI 160
                .||..::|:..|:|:||||.       .:|......:.|         :|.|..:. :|.|
Human   629 ----AYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYV---------QGNAKFVSPVRRI 680

  Fly   161 DYYVRHELYLGGVNPYDIALIYTK--EPLVFDTYVQPATLPEQDAQPEGYGT-------LYGWGN 216
               |.||.|......|||||:...  .|......:||..:|     |.|...       :.|||.
Human   681 ---VVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIP-----PTGQRVRSGEKCWVTGWGR 737

  Fly   217 VSMTAVPNYPHR--------LQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICTAD 273
                     .|.        ||:|.:.::|..||   ::..|: :....||.|.::|....|..|
Human   738 ---------RHEADNKGSLVLQQAEVELIDQTLC---VSTYGI-ITSRMLCAGIMSGKRDACKGD 789

  Fly   274 SGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVI 327
            |||||   .|....:...|:.||||||. ..|:.|.|.|:.|||.|..||::.:
Human   790 SGGPL---SCRRKSDGKWILTGIVSWGH-GSGRPNFPGVYTRVSNFVPWIHKYV 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	73/266 (27%)
CG7142	NP_650703.1	Tryp_SPc	84..323	CDD:214473	71/263 (27%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010