DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and OVCH1

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:XP_024304736.1 Gene:OVCH1 / 341350 HGNCID:23080 Length:1120 Species:Homo sapiens


Alignment Length:367 Identity:106/367 - (28%)
Similarity:158/367 - (43%) Gaps:66/367 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 SYRCIYSVL-----------LSTIASIMVVLSSASSGSIQLPTVRKCGGGRSAGAAHTMAMNLAA 57
            |..|||..:           |:.:..::.:.|..||.::.:...:..|..|..|..       |.
Human   505 SPNCIYDAVVIYGDSEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFK-------AR 562

  Fly    58 YGLL---------------ENRISTLEA---------PRQTHW-TKKFLAKREATPHSAPYVVSI 97
            :.:|               .|.:||::|         |....| :::.....||.||..|:.|.:
Human   563 FTILPSESLNKFEPKLPPQNNPVSTVKAILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGL 627

  Fly    98 QMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQKGEASNIQMRHIDY 162
            :.:...|     |.|.|||..||||||||:.......:..|:||.   ||:..:.|..|:|...:
Human   628 RFLGDYQ-----CGGAIINPVWILTAAHCVQLKNNPLSWTIIAGD---HDRNLKESTEQVRRAKH 684

  Fly   163 YVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQP---EGYGTLYGWGNVSMTAVPN 224
            .:.||.:.......|||||....||.:::.|:|..|| ..|:|   .....:.|||::|  |...
Human   685 IIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLP-HSAEPLFSSEICAVTGWGSIS--ADGG 746

  Fly   225 YPHRLQEANMPILDMELCEQIL--ARSGLPLHETNLCTG-PLTGGVSICTADSGGPLIQQCCEEH 286
            ...|||:..:.:|:.|:||...  |..| .:.|..:|.| ..:|....|..||||||:   | .|
Human   747 LASRLQQIQVHVLEREVCEHTYYSAHPG-GITEKMICAGFAASGEKDFCQGDSGGPLV---C-RH 806

  Fly   287 FEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVIS 328
            .....::.|||||| ..|.|...|.||.||..|.:||...|:
Human   807 ENGPFVLYGIVSWG-AGCVQPWKPGVFARVMIFLDWIQSKIN 847

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 86/247 (35%)
OVCH1XP_024304736.1 Tryp_SPc 58..294 CDD:238113
CUB 336..444 CDD:238001
CUB 454..565 CDD:238001 12/66 (18%)
Tryp_SPc 610..845 CDD:238113 86/251 (34%)
CUB 881..978 CDD:238001
CUB 1017..1119 CDD:238001
Blue background indicates that the domain is not in the aligned region.

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