Protein Alignment CG7142 and PRSS38

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_898885.1
• Gene: PRSS38 / 339501
• HGNCID: 29625
• Length: 326
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 95/322 - (29%)
• Similarity: 143/322 - (44%)
• Gaps: 53/322 - (16%)

  Fly    17 ASIMVVLSSASSGSIQLPTVRKCGGGRSAGAAHTMAMN--LAAYGLLENRISTLEAPRQTHWTKK 79
            ||:|..|..::.|.:.|..|  ....|.|...|....|  ::..|.:.....::|.        |
Human     5 ASVMGPLGPSALGLLLLLLV--VAPPRVAALVHRQPENQGISLTGSVACGRPSMEG--------K 59

  Fly    80 FLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVE--------NS 136
            .|....|.....|:.||:..    .|| |.|.|:|:||:|:|:||||....:.::        .:
Human    60 ILGGVPAPERKWPWQVSVHY----AGL-HVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVN 119

  Fly   137 VIVAGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQ 201
            :.|||:   |.|..|.:.: :.|..|.:.|.  :||    |:||:..|..:||...|.|..|
Human   120 LRVAGN---HTQWYEVNRV-ILHPTYEMYHP--IGG----DVALVQLKTRIVFSESVLPVCL--- 171

  Fly   202 DAQPEGYGT-----LYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTG 261
             |.||...|     ..|||.||.....:  ..|||..:|::....|..:.......:.:. ||.|
Human   172 -ATPEVNLTSANCWATGWGLVSKQGETS--DELQEMQLPLILEPWCHLLYGHMSYIMPDM-LCAG 232

  Fly   262 PLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
            .:....::|..||||||:   ||  |.::.:.|||||||: .|.....|.|:..||.|::||
Human   233 DILNAKTVCEGDSGGPLV---CE--FNRSWLQIGIVSWGR-GCSNPLYPGVYASVSYFSKWI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	80/253 (32%)
PRSS38	NP_898885.1	Tryp_SPc	60..291	CDD:238113	81/257 (32%)