Protein Alignment CG7142 and HPN

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 98/340 - (28%)
• Similarity: 138/340 - (40%)
• Gaps: 93/340 - (27%)

  Fly    43 RSAGAAHTMAMNLAAYGLLENR------ISTLEAPRQTHWTKKFLAK------------------ 83
            |:|||..|........|.|.:.      ||..:.||     .:|||.
Human   107 RTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPR-----GRFLAAICQDCGRRKLPVDRIVGG 166

  Fly    84 REATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC-------LSSPQAVENSVIVAG 141
            |:.:....|:.||::.    .| .|.|.|::::..|:||||||       ||..:....:|..|.
Human   167 RDTSLGRWPWQVSLRY----DG-AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQAS 226

  Fly   142 SHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPY----------DIALIYTKEPLVFDTYVQPA 196
            .|.:  |.|             |:..:|.||..|:          ||||::...||....|:||.
Human   227 PHGL--QLG-------------VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPV 276

  Fly   197 TLPEQ-DAQPEG-YGTLYGWGNVSMTAVPNYPHR---LQEANMPILDMELCEQILARSGLPLHET 256
            .||.. .|..:| ..|:.||||...     |..:   ||||.:||:..::|      :|...:..
Human   277 CLPAAGQALVDGKICTVTGWGNTQY-----YGQQAGVLQEARVPIISNDVC------NGADFYGN 330

  Fly   257 NL-----CTGPLTGGVSICTADSGGPLIQQCCEEHFEQAN--IVIGIVSWGKMPCGQKNAPSVFV 314
            .:     |.|...||:..|..|||||.:   ||:...:..  .:.|||||| ..|.....|.|:.
Human   331 QIKPKMFCAGYPEGGIDACQGDSGGPFV---CEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYT 391

  Fly   315 RVSAFTEWINQVIST 329
            :||.|.|||.|.|.|
Human   392 KVSDFREWIFQAIKT 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	81/270 (30%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	14/56 (25%)
		Tryp_SPc	163..400	CDD:238113	79/271 (29%)