DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and TMPRSS11E

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_054777.2 Gene:TMPRSS11E / 28983 HGNCID:24465 Length:423 Species:Homo sapiens


Alignment Length:312 Identity:78/312 - (25%)
Similarity:122/312 - (39%) Gaps:71/312 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 SIQLPTVRK----------CGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPRQTHWTKKFLAKR 84
            |:::..:.|          ||..||    .|:..:|...|..|        ..:..|        
Human   159 SVKIKKINKTETDSYLNHCCGTRRS----KTLGQSLRIVGGTE--------VEEGEW-------- 203

  Fly    85 EATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQK 149
                   |:..|:|.    .| .|.|..|:||..|:::||||.::   .:|......|..:..:.
Human   204 -------PWQASLQW----DG-SHRCGATLINATWLVSAAHCFTT---YKNPARWTASFGVTIKP 253

  Fly   150 GEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPE--QDAQP------E 206
            .:    ..|.:...:.||.|....:.|||:|.....|:.:...|....||:  .:.||      .
Human   254 SK----MKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVT 314

  Fly   207 GYGTLYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICT 271
            |:|.|...|...        :.|::|.:.::|...|.:..|.:. .:....||.|.|.|....|.
Human   315 GFGALKNDGYSQ--------NHLRQAQVTLIDATTCNEPQAYND-AITPRMLCAGSLEGKTDACQ 370

  Fly   272 ADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
            .||||||:.....:.:..|    ||||||. .|.:.|.|.|:.||:|..:||
Human   371 GDSGGPLVSSDARDIWYLA----GIVSWGD-ECAKPNKPGVYTRVTALRDWI 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 67/248 (27%)
TMPRSS11ENP_054777.2 SEA 51..147 CDD:460188
Tryp_SPc 192..420 CDD:238113 70/275 (25%)
Blue background indicates that the domain is not in the aligned region.

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