DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7142 and KLK13

DIOPT Version :9

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_056411.1 Gene:KLK13 / 26085 HGNCID:6361 Length:277 Species:Homo sapiens


Alignment Length:248 Identity:81/248 - (32%)
Similarity:116/248 - (46%) Gaps:37/248 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 PHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDI-HDQKGE 151
            |||.|:..::.:    ||.: .|.|.:::..|:|||||||.     |...:..|.|.: ..:.||
Human    44 PHSQPWQAALLV----QGRL-LCGGVLVHPKWVLTAAHCLK-----EGLKVYLGKHALGRVEAGE 98

  Fly   152 ASNIQMRHIDYYVRHELYLGGV----NPYDIALIYTKEPLVFDTYVQPATLPEQDAQPEGYGT-- 210
                |:|.:.:.:.|..|....    :.:||.|:..:.|:....|:|  |||.........||  
Human    99 ----QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQ--TLPLSHNNRLTPGTTC 157

  Fly   211 -LYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICTADS 274
             :.|||..:...| |||..||.||:.:...|.|.|:....   :.:..||.|...||...|..||
Human   158 RVSGWGTTTSPQV-NYPKTLQCANIQLRSDEECRQVYPGK---ITDNMLCAGTKEGGKDSCEGDS 218

  Fly   275 GGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVI 327
            ||||:   |.      ..:.||||||..||||.:.|.|:.|||.:..||.:.|
Human   219 GGPLV---CN------RTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 80/245 (33%)
Tryp_SPc 84..323 CDD:214473 78/242 (32%)
KLK13NP_056411.1 Tryp_SPc 38..261 CDD:238113 80/245 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.