Protein Alignment CG7142 and KLK5

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 65/285 - (22%)
• Similarity: 109/285 - (38%)
• Gaps: 77/285 - (27%)

  Fly    69 EAPRQTHWTKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLS----- 128
            |..|....:.:.:...:...|:.|:..:: ::.|:|   .||...:::..|:||||||..
Human    56 EDARSDDSSSRIINGSDCDMHTQPWQAAL-LLRPNQ---LYCGAVLVHPQWLLTAAHCRKKVFRV 116

  Fly   129 -------SPQAVENSVIVAG----SHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIY 182
                   ||.......:..|    .|..:...|.::::.:..::..:|
Human   117 RLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIR----------------- 164

  Fly   183 TKEPLVFDTYVQPATLPEQDAQP-------EGYGT---LYGWGNVSMTAVPNYPHRLQEANMPIL 237
                            |.:|.:|       ...||   :.|||......| ::|..||..|:.:|
Human   165 ----------------PTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQV-HFPKVLQCLNISVL 212

  Fly   238 DMELCEQILARSGLPLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKM 302
            ..:.||....|.   :.:|..|.|...|..| |..|||||::   |....:      |:||||..
Human   213 SQKRCEDAYPRQ---IDDTMFCAGDKAGRDS-CQGDSGGPVV---CNGSLQ------GLVSWGDY 264

  Fly   303 PCGQKNAPSVFVRVSAFTEWINQVI 327
            ||.:.|.|.|:..:..||:||.:.|
Human   265 PCARPNRPGVYTNLCKFTKWIQETI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	62/267 (23%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/11 (18%)
		Tryp_SPc	66..285	CDD:214473	60/269 (22%)