Protein Alignment CG7142 and F11

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 86/314 - (27%)
• Similarity: 140/314 - (44%)
• Gaps: 56/314 - (17%)

  Fly    23 LSSASSGSIQLPTVRKCGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPR--------QTHWTKK 79
            |..:|:||   ||  |...||...:.:|:.:     ..::|..:|...||        :..|
Human   349 LKLSSNGS---PT--KILHGRGGISGYTLRL-----CKMDNECTTKIKPRIVGGTASVRGEW--- 400

  Fly    80 FLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC---LSSPQAVENSVIVAG 141
                        |:.|::...:|.|.  |.|.|:||...||||||||   :.||:.:.   :.:|
Human   401 ------------PWQVTLHTTSPTQR--HLCGGSIIGNQWILTAAHCFYGVESPKILR---VYSG 448

  Fly   142 SHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQPE 206
            ..:..:.|.:.|...::.|   :.|:.|....:.|||||:..:..:.:....:|..||.:..:..
Human   449 ILNQSEIKEDTSFFGVQEI---IIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNV 510

  Fly   207 GYGTLY--GWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSI 269
            .|...:  |||...:.  ....:.||:|.:|::..|.|::  ...|..:....:|.|...||...
Human   511 IYTDCWVTGWGYRKLR--DKIQNTLQKAKIPLVTNEECQK--RYRGHKITHKMICAGYREGGKDA 571

  Fly   270 CTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWI 323
            |..||||||  .|  :|.|..::| ||.|||: .|.|:..|.|:..|..:.:||
Human   572 CKGDSGGPL--SC--KHNEVWHLV-GITSWGE-GCAQRERPGVYTNVVEYVDWI 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	71/245 (29%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	10/35 (29%)
		Tryp_SPc	389..619	CDD:238113	70/262 (27%)