DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and F10

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_000495.1 Gene:F10 / 2159 HGNCID:3528 Length:488 Species:Homo sapiens


Alignment Length:357 Identity:91/357 - (25%)
Similarity:148/357 - (41%) Gaps:75/357 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 STIASIMVVLSSASSGSIQLPT-VRKCGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPRQTHWT 77
            |.:.|.....:.|.:|...:|| ...||.........::|...::.|         |||....| 
Human   146 SVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSG---------EAPDSITW- 200

  Fly    78 KKFLAKREATPHSAPY-VVSIQMMTPDQG-----------------------LVH-----YCAGT 113
            |.:.| .:..|...|: ::......|::|                       |::     :|.||
Human   201 KPYDA-ADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGT 264

  Fly   114 IINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDI 178
            |::|.:||||||||.  ||....|.|...:...::.|||    :..::..::|..:......:||
Human   265 ILSEFYILTAAHCLY--QAKRFKVRVGDRNTEQEEGGEA----VHEVEVVIKHNRFTKETYDFDI 323

  Fly   179 ALIYTKEPLVFDTYVQPATLPEQD-AQP----------EGYGTLYGWGNVSMTAVPNYPHRLQEA 232
            |::..|.|:.|...|.||.|||:| |:.          .|:|..:..|..|.        ||:..
Human   324 AVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQST--------RLKML 380

  Fly   233 NMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIV 297
            .:|.:|...|:   ..|...:.:...|.|..|.....|..|||||.:.:     |:....|.|||
Human   381 EVPYVDRNSCK---LSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTR-----FKDTYFVTGIV 437

  Fly   298 SWGKMPCGQKNAPSVFVRVSAFTEWINQVIST 329
            |||: .|.:|....::.:|:||.:||::.:.|
Human   438 SWGE-GCARKGKYGIYTKVTAFLKWIDRSMKT 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 74/281 (26%)
F10NP_000495.1 GLA 25..85 CDD:214503
EGF_CA 86..122 CDD:238011
FXa_inhibition 129..164 CDD:464251 4/17 (24%)
O-glycosylated at one site 183..203 7/29 (24%)
Tryp_SPc 235..464 CDD:238113 70/251 (28%)
O-glycosylated at one site 476..485
Blue background indicates that the domain is not in the aligned region.

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