DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and F9

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_000124.1 Gene:F9 / 2158 HGNCID:3551 Length:461 Species:Homo sapiens


Alignment Length:274 Identity:81/274 - (29%)
Similarity:124/274 - (45%) Gaps:54/274 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 THWTKKF------LAKREATPHSAPYVVSIQMMTPDQGLVH-YCAGTIINEHWILTAAHCLSSPQ 131
            |..|:.|      :...:|.|...|:.|.:      .|.|. :|.|:|:||.||:|||||     
Human   215 TQSTQSFNDFTRVVGGEDAKPGQFPWQVVL------NGKVDAFCGGSIVNEKWIVTAAHC----- 268

  Fly   132 AVENSV---IVAGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPY--DIALIYTKEPLVFDT 191
             ||..|   :|||.|:|.:.:   ...|.|::...:.|..|...:|.|  ||||:...||||.::
Human   269 -VETGVKITVVAGEHNIEETE---HTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNS 329

  Fly   192 YVQPATLPEQDAQ----PEGYGTLYGWGNVSMTAVPNYPHR------LQEANMPILDMELCEQIL 246
            ||.|..:.:::..    ..|.|.:.|||.|.        |:      ||...:|::|...|   |
Human   330 YVTPICIADKEYTNIFLKFGSGYVSGWGRVF--------HKGRSALVLQYLRVPLVDRATC---L 383

  Fly   247 ARSGLPLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPS 311
            ..:...::....|.|...||...|..|||||.:.:     .|..:.:.||:|||: .|..|....
Human   384 RSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTE-----VEGTSFLTGIISWGE-ECAMKGKYG 442

  Fly   312 VFVRVSAFTEWINQ 325
            ::.:||.:..||.:
Human   443 IYTKVSRYVNWIKE 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 78/258 (30%)
F9NP_000124.1 GLA 28..92 CDD:214503
EGF_CA 93..129 CDD:238011
FXa_inhibition 134..170 CDD:464251
Tryp_SPc 227..457 CDD:238113 78/262 (30%)
Blue background indicates that the domain is not in the aligned region.

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