Protein Alignment CG7142 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 93/331 - (28%)
• Similarity: 144/331 - (43%)
• Gaps: 70/331 - (21%)

  Fly     8 IYSVLLSTIASIMVVLSSASSGSIQLPTVRKCGGGRSAGAAHTMAMNLAAYGLLENRISTLEAPR 72
            ::.:|.:.:||     .:|...||:|..:.|        ||..|..|......:.|.|.|
Human   135 LHQMLKNNMAS-----WNAVPASIKLMEISK--------AASEMLTNNCCGRQVANSIIT----- 181

  Fly    73 QTHWTKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCL-----SSPQA 132
                ..|.:..:.:...:.|:..|:|.    :|. |||..::|:..|:|:||||.     |....
Human   182 ----GNKIVNGKSSLEGAWPWQASMQW----KGR-HYCGASLISSRWLLSAAHCFAKKNNSKDWT 237

  Fly   133 VENSVIVAGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPAT 197
            |...::|...:            ..|.:...:.||.|.......||||:...|.:.|..|::...
Human   238 VNFGIVVNKPY------------MTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKIC 290

  Fly   198 LPE--------QDAQPEGYGTLYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLH 254
            |||        .:....|:||||..|        ::|..|||..:.|:|.::|....|.||. :.
Human   291 LPEAKMKLSENDNVVVTGWGTLYMNG--------SFPVILQEDFLKIIDNKICNASYAYSGF-VT 346

  Fly   255 ETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANI--VIGIVSWGKMPCGQKNAPSVFVRVS 317
            :|.||.|.::|....|..||||||      .:.:..||  ::||||||. .||:||.|.|:.||:
Human   347 DTMLCAGFMSGEADACQNDSGGPL------AYPDSRNIWHLVGIVSWGD-GCGKKNKPGVYTRVT 404

  Fly   318 AFTEWI 323
            ::..||
Human   405 SYRNWI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	77/255 (30%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188	1/6 (17%)
		Tryp_SPc	185..413	CDD:238113	77/259 (30%)