Protein Alignment CG7142 and KLK8

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 70/254 - (27%)
• Similarity: 114/254 - (44%)
• Gaps: 30/254 - (11%)

  Fly    79 KFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSH 143
            |.|...|..|||.|:..::     .||....|.|.::..:|:||||||......|.     .|.|
Human    77 KVLGGHECQPHSQPWQAAL-----FQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVR-----LGDH 131

  Fly   144 DIHDQKGEASNIQMRHIDYYVRHELYLGG---VNPYDIALIYTKEPLVFDTYVQPATLPEQDAQP 205
            .:.::.|....|.   :...:.|..|...   .:.:|:.|:..::.....:.|:|.:|.:...||
Human   132 SLQNKDGPEQEIP---VVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193

  Fly   206 EGYGTLYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSIC 270
            ....|:.|||.|: :...|:|..|..|.:.|...:.||.  |..| .:.:..:|.|. :.|...|
Human   194 GQKCTVSGWGTVT-SPRENFPDTLNCAEVKIFPQKKCED--AYPG-QITDGMVCAGS-SKGADTC 253

  Fly   271 TADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVIST 329
            ..||||||:   |:...:      ||.|||..|||:.:.|.|:..:..:.:||.::|.:
Human   254 QGDSGGPLV---CDGALQ------GITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	67/244 (27%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	67/246 (27%)