Protein Alignment CG7142 and KLK11

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 88/338 - (26%)
• Similarity: 131/338 - (38%)
• Gaps: 97/338 - (28%)

  Fly    43 RSAGAAHTMAMNLAAYGLLENRISTLEAPR----------------QTHWTKKFLAKREATPHSA 91
            :|:|...|.|....|      |.|.|:|.|                :|...|.|    |..|||.
Human    11 KSSGRGLTAAKEPGA------RSSPLQAMRILQLILLALATGLVGGETRIIKGF----ECKPHSQ 65

  Fly    92 PYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC------LSSPQAVENSVIVAGSHDIHDQKG 150
            |:..::...|.     ..|..|:|...|:||||||      |:||..|        |.|:
Human    66 PWQAALFEKTR-----LLCGATLIAPRWLLTAAHCLKPWVSLTSPTHV--------SPDL----- 112

  Fly   151 EASNIQMRHIDYYVRHELYLGGVN-----------------PY--------------DIALIYTK 184
            .:||..:.|:..|:.|   ||..|                 |:              ||.|:...
Human   113 SSSNYCLSHLSRYIVH---LGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMA 174

  Fly   185 EPLVFDTYVQPATLPEQDAQPEGYGTLYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARS 249
            .|:.....|:|.||..:.........:.|||:.|...: ..||.|:.||:.|::.:.||.....:
Human   175 SPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQL-RLPHTLRCANITIIEHQKCENAYPGN 238

  Fly   250 GLPLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFV 314
               :.:|.:|.....||...|..||||||:   |.:..:      ||:|||:.||.....|.|:.
Human   239 ---ITDTMVCASVQEGGKDSCQGDSGGPLV---CNQSLQ------GIISWGQDPCAITRKPGVYT 291

  Fly   315 RVSAFTEWINQVI 327
            :|..:.:||.:.:
Human   292 KVCKYVDWIQETM 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	75/278 (27%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	75/284 (26%)