Protein Alignment CG7142 and PRSS21

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 86/325 - (26%)
• Similarity: 137/325 - (42%)
• Gaps: 82/325 - (25%)

  Fly    45 AGAAHTMAMNLAAYGLLENRISTLEAPRQTHWTKKFLAKREATPHSAP---YVVSIQMM------ 100
            |..|..:|:.||..||.:..                  .:||.|.|.|   .|::.:::
Human     3 ARGALLLALLLARAGLRKPE------------------SQEAAPLSGPCGRRVITSRIVGGEDAE 49

  Fly   101 ---TPDQGLV-----HYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQKGEASNIQM 157
               .|.||.:     |.|..::::..|.||||||..:            ..|:.|..|..  :|.
Human    50 LGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFET------------YSDLSDPSGWM--VQF 100

  Fly   158 RHID----------YYVRH---ELYLG----GVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQP 205
            ..:.          ||.|:   .:||.    |.:||||||:....|:.:..::||..|.....:.
Human   101 GQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEF 165

  Fly   206 EGYGTLY--GWGNVSM-TAVPNYPHRLQEANMPILDMELCEQILARSGL--PLHETNLCTGPLTG 265
            |.....:  |||.:.. .|:|: ||.|||..:.|::..:|..:..:...  .:....:|.|...|
Human   166 ENRTDCWVTGWGYIKEDEALPS-PHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQG 229

  Fly   266 GVSICTADSGGPLIQQCCEEH--FEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVIS 328
            |...|..||||||   .|.::  :.|    ||:|||| :.||:.|.|.|:..:|...|||.::::
Human   230 GKDACFGDSGGPL---ACNKNGLWYQ----IGVVSWG-VGCGRPNRPGVYTNISHHFEWIQKLMA 286

  Fly   329  328
            Human   287  286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	79/282 (28%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	73/263 (28%)