Protein Alignment Vps39 and si:ch211-266g18.9

DIOPT Version :9

• Sequence 1: NP_650702.1
• Gene: Vps39 / 42192
• FlyBaseID: FBgn0038593
• Length: 876
• Species: Drosophila melanogaster
• Sequence 2: XP_017207278.2
• Gene: si:ch211-266g18.9 / 101883291
• ZFINID: ZDB-GENE-131127-382
• Length: 837
• Species: Danio rerio
• Alignment Length: 916
• Identity: 201/916 - (21%)
• Similarity: 395/916 - (43%)
• Gaps: 172/916 - (18%)

  Fly    17 IESIAAYGNHVILGTRSGQLIMYSVDEETG--------VDMRMFNKNFSRKPITQMEVIASENLL 73
            |:.:..:|.::.:||:.|.:...:|:..:.        |..|...::.:...:|.:.|:   |.|
Zfish    24 IQCLECFGKNLYIGTKEGAVEYLTVNNPSSQQSLTVREVGKRQMGRSGAIIKLTAIPVL---NHL 85

  Fly    74 FVLTDLQVQVCDIRRIESNFAFMHSAPDTKGCTLFTMDVDTPKSTTGRVATVIRVCCAIRRRLVF 138
            .||.|..:.|.::..:|: ...:...|:.   .||.:.    :|...|.:..:.|..:.|:.:..
Zfish    86 LVLWDGSITVLNMFSLEA-LPALKKIPNV---LLFAVS----ESGIQRDSAELIVASSRRKTVSV 142

  Fly   139 FFWKEDKLNSLELIIELSDVPRTLCWVGHAVCVGFKDEYVVYDISGKAPKKHNLFLTSSSISRDP 203
            :....|:...::.:: |...|..|..:|..:||...|.|.::|  .::....:|||.:
Zfish   143 YKVHVDRWECVKQVV-LPQEPVLLAALGTCLCVATCDRYFLHD--HQSQNTTDLFLHN------- 197

  Fly   204 CICLIRNNMLG--ISKDSYLVVVDPSQYKESDG------INNSTDVRPAAMDSNSSLTPLLWSSP 260
               |.:.|::.  ..|..:::        ...|      :.|.|...|          |:.....
Zfish   198 ---LGKQNIIANKCGKGEFVL--------NGPGCLGMFVMKNGTSQHP----------PVQLPDG 241

  Fly   261 LLDLVWDEPFAVGRVNNAIEVRSLVGKDTLVQTIPELQKTKFLVHADKGTIFAAATSELWCIRMV 325
            ::|.....|:.:...|.::.:.|::.:. |.||:| :...:.||..:: ::|.....|:.  |:.
Zfish   242 VMDAAVHFPYVLALQNQSVHIYSILDQQ-LKQTVP-VHNARSLVPTEE-SVFIVTDKEIQ--RLS 301

  Fly   326 EIPIQRQ--QLLQQKKFQLAIELTQISDEPAADRAQ------TIRQIHMLYAKEL--------FT 374
            .:|::.|  :|:.:::.:.|:.|        .:|.|      :.:.:|    |.|        |.
Zfish   302 PVPLEDQIHELVNRQRVEEALTL--------LERLQHLLPRDSYKDLH----KNLICTSGMIKFY 354

  Fly   375 NKEFSAAMKEFEKAAIDPYDVIRLFPNLVPEPKPG-TEDVTVPTSSTPALED--SDLENAYLALI 436
            .:.|..|.:.|.|..:||.::|.|:|.:     |. :||.|..|::....:|  :...|.:....
Zfish   355 REAFVEAKELFIKGDLDPREIISLYPAM-----PVLSEDFTPQTTAVSNAKDLWTLSRNDWPTFQ 414

  Fly   437 EYLAWARQREVVKLRDTK--SSSKSLLEIIDTTLLKCYLQ--TNDSLVAPLLRLNQCHLEESEKT 497
            :||::...    .||:.|  :..::.|:.||:.|.|.||:  .|:.|...:...|.|:|:.....
Zfish   415 QYLSFLDD----FLREVKPTAQGQTCLQDIDSALFKLYLEQGENEKLDQLVSTQNNCNLQMCVAD 475

  Fly   498 LKKHNKISELIILYQMKGKHKEA----LKLLREQAS--IEGSVLQGRKRTIRYLQELGGDHLPLI 556
            |::|.:...|.:|||.:|:|..|    :|::.:::.  ...||.|...:|:..|     :|..:|
Zfish   476 LEQHKRFFTLGLLYQSQGQHFNAIQTWIKIVEDESEDPSNTSVFQHIVKTLSNL-----EHKQII 535

  Fly   557 FEFADWVLNDNPEEGLTIFT------------DELIEV-ESLPRAKVLDFFISKHKALVIPYLEH 608
            ::|.||||..:.|.|:.|||            :|:..: .|.|.|..|             |||:
Zfish   536 WKFVDWVLRRDQEAGILIFTKTNAGNHNTFVPEEVFTILNSYPVALTL-------------YLEY 587

  Fly   609 VITEWKDGNTLLHNVLLKQYREKVQRLLAQQEKGEEVPELIPMRAKLYKMLEESNDYSPDRLLEE 673
            ::.|........|.:|:..|.:::.|.||.....|...|  .||.||.::|.:|:.|:.|::.::
Zfish   588 LVNESHSKEEKHHTMLITSYVKRILRSLADDHNNESSTE--EMRHKLQQLLWQSSFYNADQIYDQ 650

  Fly   674 FPTNILLEERALILGRLKKHDNVLSIYIHVLGDVAKATAY-----AEAHYKEDKHIFHTLIKCIL 733
            ..::.|..|:|:.||:..||...|.:.::...|...|..|     |....|..:.||.||::..|
Zfish   651 IASSSLHVEQAISLGKNGKHKKALQVLVNEEKDQQAAECYCWRTSAGRDKKFTQTIFLTLLQIYL 715

  Fly   734 IPPTQPLYDGVPLHPDFSQVNREV--ALEILNTHATRIDPFEIFEHLPDDMPMPQLEKYLEKSIR 796
                              :.:..|  |:::||.:....|...:...||:...:..:.::|.:|:|
Zfish   716 ------------------ESSHHVIAAVDLLNKNPESFDLSSVLMVLPESWSLKVVLRFLCESLR 762

  Fly   797 KMMADKHEMQMMCGFLEAESTRLENALEEQRNISFELNESSVCSECKKRFQTQSAFVRYPNGHIV 861
            ..:.||....:.....:.|:.|..:||....:...:::...||..|:||. |.:.|:|.|.|.:.
Zfish   763 GTVHDKRMRGLEMSLAKVETLRHRHALMAATHEKIQVDRGCVCHSCQKRL-TGAEFLRRPTGELT 826

  Fly   862 HLSCHD 867
            |::||:
Zfish   827 HITCHN 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps39	NP_650702.1	CNH	24..304	CDD:295303	52/295 (18%)
		Vps39_1	464..564	CDD:287352	31/107 (29%)
		Vps39_2	759..868	CDD:287353	27/109 (25%)
si:ch211-266g18.9	XP_017207278.2	CNH	31..283	CDD:321933	52/295 (18%)
		Vps39_1	440..543	CDD:313568	31/107 (29%)
		Clathrin	581..687	CDD:330899	30/120 (25%)
		Vps39_2	725..832	CDD:313569	26/107 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54136
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1627
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.950