Protein Alignment CG18599 and HGTX

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 128/593 - (21%)
• Similarity: 197/593 - (33%)
• Gaps: 226/593 - (38%)

  Fly     5 PSKYHANPLSH------------------FLALHNTQASGGGSGGGSS-----VAGLGGLGGGIH 46
            |:.|.|.|..|                  ::..|:..|:..||...::     .|.:......:|
  Fly    52 PAFYRAPPQQHPECLDYGHEAPEMDLINPYMRHHSFAAAAQGSPPSAAQRHHLAAAMSNGFADVH 116

  Fly    47 AHGQPHHAALAAAAAAAVAVSAGQSSYQMEHQQQHHQLQQQQQQQQHHHHQQLHTHHQDGHHPHP 111
            ||      |:|||            .||                      |||..:|........
  Fly   117 AH------AMAAA------------DYQ----------------------QQLADYHSAAAAAAV 141

  Fly   112 PTPTTGNNNNNSSSSSNSS-------SHNSNSNHREQLAAAAATATSHAQLIEAAA---AHSS-- 164
            ......|||||||:::|||       :|.......:..:.....|:|......:.:   .|:|
  Fly   142 YANNNNNNNNNSSNNNNSSPLMLLKAAHGGGLKDSDSPSTTPPPASSRLHSDSSPSPRYEHNSSP 206

  Fly   165 -LDVGKSFTIA--------------------------AILGLQSQRKDY--------------NN 188
             :|..||:.::                          :...|.|||..:              |:
  Fly   207 GVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNPLALHNANH 271

  Fly   189 AINLSLHDNNN---------IIG-----------------------DDNNKCYTSNPNNN-NNNN 220
            |.|...|:|||         .:|                       ..|...|:.:||:: .::.
  Fly   272 AGNPGCHNNNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDR 336

  Fly   221 NNGGSNSG------NNNSSPSVNNFNCDSV-----------------------------AGNGRY 250
            .:|||:|.      |.||..:.|....|::                             ||..:|
  Fly   337 GSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQY 401

  Fly   251 L----------HGGH--QHPHPHQAGFAAVAAAVGAAPSALQ-----SLQQLHQQHHAQQQATLS 298
            |          |.||  ...|.:..|...:.|...|....|.     :|.|.||.|
  Fly   402 LSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHH--------- 457

  Fly   299 FQREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVW 363
                    .|:.|.. |.|..|..|:.:|:..||..||:.:|:.||||..||:.|.::|:|||||
  Fly   458 --------PSNDKDG-KKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVW 513

  Fly   364 FQNRRIKWRKHHLELTQQRLALIRQTQLPG-----TSLLGNQVSVSANAAHSVSTERTNGCSAAS 423
            |||||.||||.|  ..:...|..:|..:.|     .|...:..:.|.:...|.:..:....:::.
  Fly   514 FQNRRTKWRKRH--AAEMATAKRKQDDMGGDNDGDCSETMDSDNESLDMGESPAQNKRCRSNSSG 576

  Fly   424 PSLQEEDN 431
            .|.|::||
  Fly   577 SSQQQQDN 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	29/55 (53%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	32/208 (15%)
		Homeodomain	465..523	CDD:459649	30/57 (53%)