Protein Alignment CG18599 and Tlx1

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001102636.1
• Gene: Tlx1 / 499361
• RGDID: 1563655
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 447
• Identity: 96/447 - (21%)
• Similarity: 134/447 - (29%)
• Gaps: 161/447 - (36%)

  Fly     9 HANPLSHFL-ALHNTQASGGGSGGGSSVA----GLGGLGGGIHAHGQPHHAALAAAAAAAVAVSA 68
            ||.|:|..: .:.|:...||..|..|.:.    |||.|.||.:.:|....||.|.|.......:.
  Rat    13 HAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAGAGAGGTGAYGTG 77

  Fly    69 GQSSYQMEHQQQHHQLQQQQQQQQHHHHQQLHTHHQDGHHPHPPTPTTGNNNNNSSSSSNSSSHN 133
            |                                       |..|....|......|....:.|:|
  Rat    78 G---------------------------------------PGGPGGPAGGGGGACSMGPLAGSYN 103

  Fly   134 SNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLSLHDNN 198
                                                                    :|::|
  Rat   104 --------------------------------------------------------VNMAL---- 108

  Fly   199 NIIGDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSVNNFNCDSVAG-----NGRYLHGGHQHP 258
                                   .||...|..............|.||     ..|.|.|...||
  Rat   109 -----------------------AGGPGPGGGGGGAGAGGAGALSAAGVIRVPAHRPLAGAVAHP 150

  Fly   259 HPHQAGFAAVAAAVGAAPS--ALQSLQQLHQQHHAQQQATLSFQREKLKSDSHK-KSALKNKRVR 320
            .|...|...|       ||  |:..:..|........::...:.:::.....:: ::..|.|:.|
  Rat   151 QPLATGLPTV-------PSVPAVPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPR 208

  Fly   321 TIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLE----LTQQ 381
            |.||..|:..||..|.||:|:...||..||..||:|:||||.||||||.|||:...|    ..||
  Rat   209 TSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQ 273

  Fly   382 RLALIRQTQ-----------LPGTSLLGNQVSVSA----NAAHSVSTERTNGCSAAS 423
            ...::.|.|           ||...|..:..|:.|    ......||:.|:..|.||
  Rat   274 ANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVAS 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	31/55 (56%)
Tlx1	NP_001102636.1	Homeodomain	205..261	CDD:459649	31/55 (56%)