Protein Alignment CG18599 and NKX3-1

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_006158.2
• Gene: NKX3-1 / 4824
• HGNCID: 7838
• Length: 234
• Species: Homo sapiens
• Alignment Length: 187
• Identity: 52/187 - (27%)
• Similarity: 76/187 - (40%)
• Gaps: 38/187 - (20%)

  Fly   233 SPSVNNFNCDSVAGNGRYLHGG----------HQHPHPHQAGFAAVAAAVG--------AAPSAL 279
            |..:.:|....:..:|....||          ...|.|...|..:.|.|..        |||...
Human    23 SKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLSTGPRAAPEEA 87

  Fly   280 QSLQQLHQQHHAQQQATLSFQREKLKSDSHKKSAL---------KNKRVRTIFTPEQLECLEAEF 335
            ::|.:...:.|....         |....:...||         ..||.|..|:..|:..||.:|
Human    88 ETLAETEPERHLGSY---------LLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKF 143

  Fly   336 ERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLP 392
            ..|:|:..|||.:||..|||||.|||:||||||.|.::.  :|:.:...|.:.:.||
Human   144 SHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK--QLSSELGDLEKHSSLP 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	30/55 (55%)
NKX3-1	NP_006158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		21/116 (18%)
		Homeodomain	125..181	CDD:459649	30/55 (55%)