Protein Alignment CG18599 and MSX2

DIOPT Version :9

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 66/242 - (27%)
• Similarity: 94/242 - (38%)
• Gaps: 75/242 - (30%)

  Fly   232 SSPSVNN--FNCDS-----VAGNGRYLHGGHQHPHPHQAGFAA-------------VAAAVG--- 273
            :|||..|  |:.|.     |||.|         |.|..|..||             |.|.:.
Human     2 ASPSKGNDLFSPDEEGPAVVAGPG---------PGPGGAEGAAEERRVKVSSLPFSVEALMSDKK 57

  Fly   274 ----AAP------SALQSLQQLHQQHHAQQQA------TLSFQREKLKSDSHKKSAL-------- 314
                |:|      ||..:|:.|....|..::|      ...|:...:||::.:..|.
Human    58 PPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRY 122

  Fly   315 ------------------KNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVK 361
                              .|::.||.||..||..||.:|.::||:...||...:.:|.|||.|||
Human   123 SPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVK 187

  Fly   362 VWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSVSANAA 408
            :||||||.| .|...|...::|.:..:..||.:..|...:|....||
Human   188 IWFQNRRAK-AKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAA 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	27/51 (53%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		19/77 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		1/30 (3%)
		Homeobox	145..199	CDD:365835	27/54 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810