DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18599 and nkx6.1

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001002475.1	Gene:	nkx6.1 / 436748	ZFINID:	ZDB-GENE-040718-178	Length:	312	Species:	Danio rerio

Alignment Length:	218	Identity:	67/218 - (30%)
Similarity:	90/218 - (41%)	Gaps:	56/218 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 SSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAA--PSALQSL--------QQLH 286
            |.|||.......::|..|:  .....|.|....|:..||||..|  |..|..|        ..:.
Zfish    97 SRPSVACSPAGILSGLPRF--SSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGRTPIFWPGVM 159

  Fly   287 QQHHAQQQATLSFQREKLKSDSHKKSAL-----KNKRVRTIFTPEQLECLEAEFERQQYMVGPER 346
            |..|        ::..:.....|:.|.|     |.|..|..|:.:|:..||..||:.:|:.||||
Zfish   160 QSPH--------WRDARFACSPHQNSVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPER 216

  Fly   347 LYLAHTLKLTEAQVKVWFQNRRIKWRKHH-LELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHS 410
            ..||::|.:||:||||||||||.||||.| .|:                        .||.....
Zfish   217 ARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEM------------------------ASAKKKQD 257

  Fly   411 VSTERTNGCSAASPSLQEEDNED 433
            ..|||..|.|      :.||::|
Zfish   258 SETERLKGAS------ENEDDDD 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	28/51 (55%)
nkx6.1	NP_001002475.1	Homeobox	189..242	CDD:278475	28/52 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810