Protein Alignment CG18599 and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 63/279 - (22%)
• Similarity: 100/279 - (35%)
• Gaps: 83/279 - (29%)

  Fly   114 PTTGNNNNNSSSSSNSSSHNSNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVGKSFTIAAILG 178
            |.||.::..::.:.....| :.:.|....|||||.|.:      ||||...:..|.|
  Rat    50 PPTGPSSQAAAVAGMQPPH-AMAGHNAAAAAAAAAAAA------AAAATYHMPPGVS-------- 99

  Fly   179 LQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSVNNFNCDS 243
                                            ..|::...:..|||  .||....|:..:.....
  Rat   100 --------------------------------QFPHSAMGSYCNGG--LGNMGELPAYTDGMRGG 130

  Fly   244 VAGNGRYLHGGHQHP-HPHQAGFAAVAAAVGAA--------PSALQSLQQLHQQHHAQQQATLSF 299
            .|......:|.:..| :...:.|...:|.|..|        ..|.:||..||
  Rat   131 AAAAATGWYGANTDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLAPLH------------- 182

  Fly   300 QREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWF 364
                        :|...::.|.:|:..|:..||..|::|:|:..|||.:||..:.||..|||:||
  Rat   183 ------------AAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWF 235

  Fly   365 QNRRIKWRKHHLELTQQRL 383
            ||.|.|.::...:...|:|
  Rat   236 QNHRYKMKRQAKDKAAQQL 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	24/55 (44%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	24/55 (44%)