Protein Alignment CG18599 and HMX3

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001099044.1
• Gene: HMX3 / 340784
• HGNCID: 5019
• Length: 357
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 85/375 - (22%)
• Similarity: 133/375 - (35%)
• Gaps: 115/375 - (30%)

  Fly   107 HHPHPPTPTTGNNNNNSSSSSNSSSHNSNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVG--- 168
            ||..||.|........:.:|:.:             |||||.|.:....:|.||..:...||
Human    41 HHRPPPKPQPPPRTLFAPASAAA-------------AAAAAAAAAAKGALEGAAGFALSQVGDLA 92

  Fly   169 --------KSFTIAAILGLQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNN----- 220
                    :.|.:.|....:|....|.                     ||..|...:...
Human    93 FPRFEIPAQRFALPAHYLERSPAWWYP---------------------YTLTPAGGHLPRPEASE 136

  Fly   221 ----NNGGSNSGNNNSSP------SVNNFNCDSVAGNGRYLH--GGHQHPHPHQAGFAAVAAAVG 273
                .:....||.:..||      ..::...||.:.:...|.  ...:.....:|...|..|:||
Human   137 KALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVG 201

  Fly   274 AAPSALQSLQQLHQQHHAQQQATLSFQREKLKSDS-HKKSALKNKRVRTIFTPEQLECLEAEFER 337
            ||                  .||...:..|..::| .||.|.:.|:.||:|:..|:..||:.|:.
Human   202 AA------------------AATPGAEDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDM 248

  Fly   338 QQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKH---HLELTQQRLALIRQTQLPGTSLLGN 399
            ::|:...||..||.:|.|||.|||:||||||.||::.   .||
Human   249 KRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELE---------------------- 291

  Fly   400 QVSVSANAAHSVSTERTNGCSAASPSLQEEDNEDSKHSLSLSGALPPLSR 449
                :||.:|:.:..     ....|.|..|::.....:.:.:||..|:|:
Human   292 ----AANLSHAAAQR-----IVRVPILYHENSAAEGAAAAAAGAPVPVSQ 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	28/55 (51%)
HMX3	NP_001099044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..229		21/117 (18%)
		Homeodomain	228..284	CDD:459649	28/55 (51%)