DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18599 and dlx3b

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_571397.2	Gene:	dlx3b / 30585	ZFINID:	ZDB-GENE-980526-280	Length:	269	Species:	Danio rerio

Alignment Length:	246	Identity:	65/246 - (26%)
Similarity:	114/246 - (46%)	Gaps:	53/246 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 GSNSGNNNS--SPSVNNFNCDSVAGNGRYLHGGHQH----PHP------HQAGFAAVAAAVGAAP 276
            ||.|.:..|  ||::.    :|.|.:..|....|::    |:|      ||...:.:.|..||.|
Zfish    19 GSMSCHPTSKDSPTLP----ESSATDMGYYSSHHEYYQSPPYPQQMNSYHQFNLSGMGATPGAYP 79

  Fly   277 SALQSLQQLHQQHHAQQQATLSFQREKLKSDSHKKSALKN------KRVRTIFTPEQLECLEAEF 335
            :..:.....::|:....:...:..:..:|.:...:..:.|      ::.|||::..||..|:..|
Zfish    80 TKTEYPYNTYRQYGHYNRDLQTPPQSAVKEEPETEVRMVNGKPKKIRKPRTIYSSYQLAALQRRF 144

  Fly   336 ERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQ 400
            ::.||:..|||..||..|.||:.|||:||||||.|::|           |.:..::|
Zfish   145 QKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK-----------LYKNGEVP-------- 190

  Fly   401 VSVSANAAHSVSTERTNGCSAASPSLQEEDNEDSKHSLSLS-GAL--PPLS 448
            :..|.||:.|::..     |..||::.    :::.||..:: |.:  ||||
Zfish   191 LEHSPNASDSMACN-----SPPSPAVW----DNNAHSSQVNRGQIPQPPLS 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	27/51 (53%)
dlx3b	NP_571397.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41		8/25 (32%)
		DLL_N	28..104	CDD:289198	15/79 (19%)
		Homeobox	128..181	CDD:278475	27/52 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..242		14/51 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	250..269
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810