DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18599 and dlx2b

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_571372.1	Gene:	dlx2b / 30557	ZFINID:	ZDB-GENE-980526-18	Length:	276	Species:	Danio rerio

Alignment Length:	187	Identity:	46/187 - (24%)
Similarity:	81/187 - (43%)	Gaps:	38/187 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 HQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLSFQREKLKSDSHKKSALKNKRV 319
            |..|..:..|:|:...|.|...::........::..::.:..:...:.|           |.::.
Zfish    75 HYSPKAYDLGYASSYGAYGTYGASSSPTPTEPEKEESEPEVRMVNGKPK-----------KVRKP 128

  Fly   320 RTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLA 384
            |||::..||..|:..|::.||:..|||..||.:|.||:.|||:||||||.|::|
Zfish   129 RTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKK----------- 182

  Fly   385 LIRQTQLPGTSLLGNQVSVSA----------------NAAHSVSTERTNGCSAASPS 425
            |.:..::|....:.:..|.|:                |...:||.:.|...:..:||
Zfish   183 LWKNGEIPADQQVASGDSPSSSPPPQAGWDFPPNPTQNDGDTVSEQPTGPPNTTAPS 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	27/51 (53%)
dlx2b	NP_571372.1	DLL_N	29..102	CDD:289198	6/26 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..123		0/25 (0%)
		Homeobox	128..181	CDD:278475	27/52 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..238		6/46 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810