Protein Alignment CG18599 and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_234082.6
• Gene: Nkx1-1 / 298981
• RGDID: 1564874
• Length: 443
• Species: Rattus norvegicus
• Alignment Length: 340
• Identity: 83/340 - (24%)
• Similarity: 115/340 - (33%)
• Gaps: 103/340 - (30%)

  Fly   129 SSSHNSNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLS 193
            ::|..|.....|:.|.:|||.      :.||........|.|:           |.|...|...|
  Rat   127 AASGRSPRAELERRALSAATG------VAAATGAEPTSTGDSY-----------RADEAEANGYS 174

  Fly   194 LHDNNNIIGDDNNKC-----------------YTSNPNNNNNN---NNNGGSNSGNNNSSPSVNN 238
            .....:...|..::.                 .|..|...:..   ..:|.|.:....:|| |:.
  Rat   175 SGSGRSPTADSEDEAPEEDEDEDQAPEVQDVQGTEEPRGGSGGLGARGSGCSGAAEVEASP-VDE 238

  Fly   239 FNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLSFQREK 303
            .......||.           |...|....||..|.|.|             ..|.|.::.:.::
  Rat   239 AAAPGPRGNS-----------PGAPGPPVTAAGAGNAGS-------------TPQGAAVATKPKR 279

  Fly   304 LKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRR 368
            .::.|..||. |.:|.||.||.|||..||.:|:..:|:...|||.||.:|.|||.|||:||||||
  Rat   280 KRTGSDSKSG-KPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRR 343

  Fly   369 IKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHSVSTERTNGCSAASPSLQEEDNED 433
            .||:|                |.||..                ::..|.|.....|.
  Rat   344 TKWKK----------------QNPGAD----------------TSAPTGGGGGPGPG-------- 368

  Fly   434 SKHSLSLSGALPPLS 448
            :.....|.|.|.|||
  Rat   369 AGPGAGLPGGLSPLS 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	32/55 (58%)
Nkx1-1	XP_234082.6	Homeodomain	292..348	CDD:459649	32/55 (58%)