Protein Alignment CG18599 and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 279
• Identity: 61/279 - (21%)
• Similarity: 101/279 - (36%)
• Gaps: 82/279 - (29%)

  Fly   114 PTTGNNNNNSSSSSNSSSHNSNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVGKSFTIAAILG 178
            |.:|.::..::.::.....::.:.|....|||||.|.:      ||||...:..|.|
Mouse    50 PPSGPSSQAAAVAAGMQPPHAMAGHNAAAAAAAAAAAA------AAAATYHMPPGVS-------- 100

  Fly   179 LQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSVNNFNCDS 243
                                            ..|::...:..|||  .||....|:..:.....
Mouse   101 --------------------------------QFPHSAMGSYCNGG--LGNMGELPAYTDGMRGG 131

  Fly   244 VAGNGRYLHGGHQHP-HPHQAGFAAVAAAVGAA--------PSALQSLQQLHQQHHAQQQATLSF 299
            .|......:|.:..| :...:.|...:|.|..|        ..|.:||..||
Mouse   132 AAAAATGWYGANTDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLAPLH------------- 183

  Fly   300 QREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWF 364
                        :|...::.|.:|:..|:..||..|::|:|:..|||.:||..:.||..|||:||
Mouse   184 ------------AAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWF 236

  Fly   365 QNRRIKWRKHHLELTQQRL 383
            ||.|.|.::...:...|:|
Mouse   237 QNHRYKMKRQAKDKAAQQL 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	24/55 (44%)
Nkx2-4	NP_075993.1	Homeodomain	189..245	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		2/11 (18%)