DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18599 and Vax1

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_033527.1	Gene:	Vax1 / 22326	MGIID:	1277163	Length:	338	Species:	Mus musculus

Alignment Length:	265	Identity:	74/265 - (27%)
Similarity:	105/265 - (39%)	Gaps:	64/265 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 PSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLS 298
            |...:..|.|.....|.....|:...       .:..|.|:.|:|.     |.:...|...:..|
Mouse     5 PDKMDVRCHSDTEAARVSKNAHKESR-------EIKGAEGSLPAAF-----LKEPQGAFSGSGAS 57

  Fly   299 FQREKLKSDS-------------HKKSALKN------------KRVRTIFTPEQLECLEAEFERQ 338
            ....|.||:|             ..|.:::.            ||.||.||.|||..||.||:|.
Mouse    58 EDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRC 122

  Fly   339 QYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQR------------LALIRQTQL 391
            ||:||.||..||..|.|:|.||||||||||.|.:|...:.::.|            |.|:.|.:|
Mouse   123 QYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRL 187

  Fly   392 ---PG---------TSLLGNQV---SVSANAAHSVSTERTNGCSAASPSLQEEDNEDSKHSLSLS 441
               ||         |..||:.:   |:.|..|.:.:.......:||:.:........|:|..::.
Mouse   188 LSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAAATAPGPAGAASQHQPAVG 252

  Fly   442 GALPP 446
            ||..|
Mouse   253 GAPGP 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	34/51 (67%)
Vax1	NP_033527.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		16/75 (21%)
		Homeobox	103..156	CDD:306543	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..269		5/19 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..338
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24339
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910