Protein Alignment CG18599 and EMX1

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 81/283 - (28%)
• Similarity: 107/283 - (37%)
• Gaps: 109/283 - (38%)

  Fly   148 TATSHAQLIEAAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSN 212
            ||.:.|.:.:.||.       :.|||.:::.     ||
Human    27 TAPAAATMFQPAAK-------RGFTIESLVA-----KD--------------------------- 52

  Fly   213 PNNNNNNNNNGGSNSGN-----------------NNSSPS------VNNFNCDSVAGNGRYLHGG 254
               .......||..:|:                 |...||      |:.|...:.||.||.|:||
Human    53 ---GGTGGGTGGGGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGG 114

  Fly   255 HQ--------HP----HP-HQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATL--------- 297
            .:        ||    || ||         :||:|     ||..|....||.:..|
Human   115 PELVFPEAMNHPALTVHPAHQ---------LGASP-----LQPPHSFFGAQHRDPLHFYPWVLRN 165

  Fly   298 -----SFQREKLKSDS---HKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLK 354
                 .||...:..|.   |...|.|.||:||.|:|.||..||..||:..|:||.||..||.:|.
Human   166 RFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLS 230

  Fly   355 LTEAQVKVWFQNRRIKWRKHHLE 377
            |:|.||||||||||.|:::..||
Human   231 LSETQVKVWFQNRRTKYKRQKLE 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	33/55 (60%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		2/5 (40%)