Protein Alignment CG18599 and Nkx2-6

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_035050.2
• Gene: Nkx2-6 / 18092
• MGIID: 97351
• Length: 289
• Species: Mus musculus
• Alignment Length: 292
• Identity: 70/292 - (23%)
• Similarity: 110/292 - (37%)
• Gaps: 54/292 - (18%)

  Fly   171 FTIAAILGLQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPS 235
            |::|.||.|:.|:||........||.|            ...|.....|..:|...|.:...:..
Mouse    11 FSVADILRLECQQKDSKTLSQWELHRN------------PVKPRYLRMNQESGWFESSDRAQAVP 63

  Fly   236 VNNFNC--DSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLS 298
               |.|  ::|...|       .:|             ||...:...::.:|..::....:...:
Mouse    64 ---FRCTWETVLEMG-------SNP-------------VGEPQTPPGTISRLGARNPMTDRGVGN 105

  Fly   299 FQREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVW 363
            ...:..:...........::.|.:|:..|:..||..|::|:|:..|||.:||..|:||..|||:|
Mouse   106 LSGDMRRGGPVSTRTRPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLASALQLTSTQVKIW 170

  Fly   364 FQNRRIKWRKHH----LELTQQRLALIRQTQLP-----GTSLLGNQVSVSANAAHSVSTERTNGC 419
            |||||.|.:...    |||....|| .|:..:|     |...|...|:.......:.|.....|.
Mouse   171 FQNRRYKSKSQRQDQTLELAGHPLA-PRRVAVPVLVLDGKPCLDPDVAAFLGPYKATSPYSCFGG 234

  Fly   420 SAASPSLQEEDNEDSKHSLSLS---GALPPLS 448
            .|.:|    .|...:....|.|   |.|.||:
Mouse   235 YAGTP----YDASYASRCTSASAGPGPLTPLA 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	26/55 (47%)
Nkx2-6	NP_035050.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..125		5/69 (7%)
		Homeodomain	124..179	CDD:459649	26/54 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..289		2/4 (50%)