DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18599 and DLX3

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_005211.1	Gene:	DLX3 / 1747	HGNCID:	2916	Length:	287	Species:	Homo sapiens

Alignment Length:	228	Identity:	57/228 - (25%)
Similarity:	97/228 - (42%)	Gaps:	57/228 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 NNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLSFQR 301
            :.||.:.:||.|.|                        :|.:..:....::|:.|.::..|..|.
Human    67 HQFNLNGLAGTGAY------------------------SPKSEYTYGASYRQYGAYREQPLPAQD 107

  Fly   302 E-KLKSDSHKKSALKN------KRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQ 359
            . .:|.:...:..:.|      ::.|||::..||..|:..|::.||:..|||..||..|.||:.|
Human   108 PVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQ 172

  Fly   360 VKVWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHSVSTERTNGCS---- 420
            ||:||||||.|::|           |.:..::|......|..|::.|:..|.:...|:..|
Human   173 VKIWFQNRRSKFKK-----------LYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAP 226

  Fly   421 -----------AASPSLQEEDNEDSKHSLSLSG 442
                       :||||..::......|:.:|||
Human   227 ARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSG 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	27/51 (53%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..39
		DLL_N	27..107	CDD:403572	10/63 (16%)
		COG5576	<109..232	CDD:227863	38/133 (29%)
		homeobox	129..188		28/69 (41%)
		Homeobox	132..186	CDD:395001	27/53 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	195..287		14/65 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810