Protein Alignment CG18599 and NKX6-3

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 71/238 - (29%)
• Similarity: 88/238 - (36%)
• Gaps: 103/238 - (43%)

  Fly   223 GGSNSGNNNSSPSVNNFNCDSVAGN-------------GRYLHGGHQHPHPHQAGFAAVAAAVGA 274
            ||.:|.....||.|.||   |.|||             |:...||.|               ...
Human    81 GGLSSQGVYYSPQVGNF---SKAGNEYPTRTRNCWADTGQDWRGGRQ---------------CSN 127

  Fly   275 APSALQSLQQLHQQHHAQQQATLSFQREKLKSDS-HKKSALKNKRVRTIFTPEQLECLEAEFERQ 338
            .|..|                          ||| |||     |..|..||..|:..||..||:.
Human   128 TPDPL--------------------------SDSIHKK-----KHTRPTFTGHQIFALEKTFEQT 161

  Fly   339 QYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSV 403
            :|:.||||..||::|.:||:||||||||||.||||        :.||
Human   162 KYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK--------KSAL------------------ 200

  Fly   404 SANAAHSVSTERTNGCSAA------SPSLQEEDNEDSKHSLSL 440
                ..|.||.|..|.:.|      :||    :|||.:::..|
Human   201 ----EPSSSTPRAPGGAGAGAGGDRAPS----ENEDDEYNKPL 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	31/55 (56%)
NKX6-3	NP_001351770.1	Homeodomain	138..196	CDD:459649	33/62 (53%)