DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18599 and Dlx5

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_034186.2	Gene:	Dlx5 / 13395	MGIID:	101926	Length:	289	Species:	Mus musculus

Alignment Length:	352	Identity:	80/352 - (22%)
Similarity:	119/352 - (33%)	Gaps:	133/352 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 HHPHPPTPTTGNNNNNSSSSSNSSSHNSNSNHREQLAAAAATATSHAQLIEAAAAHSSLDVGKSF 171
            |||...:||.      ..||:..|.:.|           .|.|..|......:|::     ||:.
Mouse    28 HHPSQESPTL------PESSATDSDYYS-----------PAGAAPHGYCSPTSASY-----GKAL 70

  Fly   172 TIAAILGLQSQRKDYNNAINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSV 236
                                                    ||.....:..||
Mouse    71 ----------------------------------------NPYQYQYHGVNG------------- 82

  Fly   237 NNFNCDSVAG--NGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLSF 299
                  |.||  ...|...|:..|: ||.|     .|....|||.           :|.:..::.
Mouse    83 ------SAAGYPAKAYADYGYASPY-HQYG-----GAYNRVPSAT-----------SQPEKEVAE 124

  Fly   300 QREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWF 364
            ...::.:...||.    ::.|||::..||..|:..|::.||:..|||..||.:|.||:.|||:||
Mouse   125 PEVRMVNGKPKKV----RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWF 185

  Fly   365 QNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHSVSTERTNGC-SAASPSLQE 428
            ||:|.|.:|           :::..::|              ..||.|:.....| |..||::.|
Mouse   186 QNKRSKIKK-----------IMKNGEMP--------------PEHSPSSSDPMACNSPQSPAVWE 225

  Fly   429 EDNEDSKHSLS-LSGALPPLSRAQSES 454
            .  :.|..||| ...|.||.|.....|
Mouse   226 P--QGSSRSLSHHPHAHPPTSNQSPAS 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	26/51 (51%)
Dlx5	NP_034186.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		8/26 (31%)
		DLL_N	32..118	CDD:403572	29/183 (16%)
		Homeobox	140..194	CDD:395001	26/53 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..253		18/69 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	270..289
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810