Protein Alignment CG18599 and Nkx2-5

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_446103.2
• Gene: Nkx2-5 / 114109
• RGDID: 620520
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 245
• Identity: 61/245 - (24%)
• Similarity: 100/245 - (40%)
• Gaps: 67/245 - (27%)

  Fly   258 PHPHQAGFAAVAAAVGAAPS------ALQSLQQLHQQHH----------AQQQATLSFQR----E 302
            |.....|.|.:.|.:|.|||      |..:....:.:.:          |.::...:.|:    :
  Rat    58 PEAAAPGLAELRAELGPAPSPPKCSPAFPTAPTFYPRAYGDPDPAKDPRADKKELCALQKAVELD 122

  Fly   303 KLKSD-SHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQN 366
            |.::| :.:..|.:.::.|.:|:..|:..||..|::|:|:..|||..||..||||..|||:||||
  Rat   123 KAETDGAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQN 187

  Fly   367 RRIKWRKHHLELTQQRL-------------ALIRQTQLPGTSLLGNQVS------VSANA----A 408
            ||.|.::...:.|.:.|             .|:|.    |...||:..:      |..||    |
  Rat   188 RRYKCKRQRQDQTLELLGPPPPPARRIAVPVLVRD----GKPCLGDSAAYAPAYGVGLNAYGYNA 248

  Fly   409 H------SVSTERTNGCSAASPSLQEEDNEDSKHSLSLSGALPPLSRAQS 452
            :      ..:......|:||.|:             :...|.||.:.|.|
  Rat   249 YPYPGYGGAACSPAYSCAAAYPA-------------APPAAQPPAAAANS 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	27/55 (49%)
Nkx2-5	NP_446103.2	Homeodomain	144..194	CDD:459649	26/49 (53%)