Protein Alignment CG18599 and CDX4

DIOPT Version :9

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 84/395 - (21%)
• Similarity: 120/395 - (30%)
• Gaps: 179/395 - (45%)

  Fly    29 SGGGSSVAGLGGLGGGIHAHGQPHHAALAAAAAAAVAVSAGQSSYQMEHQQQHHQLQQQQQQQQH 93
            |.||...||.||.|||    |.|..|:..|||.|.                             .
Human    20 SPGGDGTAGTGGTGGG----GSPMPASNFAAAPAF-----------------------------S 51

  Fly    94 HHHQQLHTHHQDGHHP------------------HP-PTPTTGNNNNNSSSSSNSSSHNSNSNHR 139
            |:....|....|.|.|                  :| |:.|.|....|..:||
Human    52 HYMGYPHMPSMDPHWPSLGVWGSPYSPPREDWSVYPGPSSTMGTVPVNDVTSS------------ 104

  Fly   140 EQLAAAAATATSHAQLIEAAAAHSSLDVGKSFTIAAILGLQSQRKDYNNAINLSLHDNNNIIGDD 204
                .||..:|                                  ||:|            :|.
Human   105 ----PAAFCST----------------------------------DYSN------------LGP- 118

  Fly   205 NNKCYTSNPNNNNNNNNNGGSNSGNNNSSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVA 269
                             .||..||::                            .|.|||.:.|.
Human   119 -----------------VGGGTSGSS----------------------------LPGQAGGSLVP 138

  Fly   270 AAVGAAPSALQSLQQLHQQHHAQQQATLSFQREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAE 334
            ...|||.::..|         ..:.:..::.|:.::...  |:..|.| .|.::|..|...||.|
Human   139 TDAGAAKASSPS---------RSRHSPYAWMRKTVQVTG--KTRTKEK-YRVVYTDHQRLELEKE 191

  Fly   335 FERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGN 399
            |...:|:....:..||..|.|:|.|||:||||||.|.||    :.:::   |.|.:..|.|:..:
Human   192 FHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERK----MIKKK---ISQFENSGGSVQSD 249

  Fly   400 QVSVS 404
            ..|:|
Human   250 SDSIS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	23/51 (45%)
CDX4	NP_005184.1	Caudal_act	13..162	CDD:309740	49/291 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		12/23 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		13/71 (18%)
		Homeobox	177..229	CDD:306543	23/51 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		5/17 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810