Protein Alignment CG18599 and CDX2

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_011533177.1
• Gene: CDX2 / 1045
• HGNCID: 1806
• Length: 321
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 81/300 - (27%)
• Similarity: 111/300 - (37%)
• Gaps: 82/300 - (27%)

  Fly   130 SSHNSNSNHREQLAAAAATATSHAQ--------LIEAAAAHSSLD----VGKSFTIAAILGLQSQ 182
            |.:.|:..|...|..|.....|..|        :..||||.::||    .|.|:..|....|
Human    12 SMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPL--- 73

  Fly   183 RKDYNN--------AINLSLHDNNNIIGDDNNKCYTSNPNNNNNNNNNGGS-NSGNNNSSPSVNN 238
            |:|:|.        |.|...|                        ..|||| .:....|||:
Human    74 REDWNGYAPGGAAAAANAVAH------------------------GLNGGSPAAAMGYSSPA--- 111

  Fly   239 FNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVG------------AAPSALQSLQQLHQQHH- 290
                      .|....|.|.|||... ||.:.|.|            ||.:|.:.|....|:.:
Human   112 ----------DYHPHHHPHHHPHHPA-AAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNL 165

  Fly   291 ---AQQQATLSFQREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHT 352
               .::.|..|...:.|.|.|.........:.|.::|..|...||.||...:|:....:..||.|
Human   166 CEWMRKPAQQSLGSQALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAAT 230

  Fly   353 LKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLP 392
            |.|:|.|||:||||||.|.||.:.:..||:    :|.|.|
Human   231 LGLSERQVKIWFQNRRAKERKINKKKLQQQ----QQQQPP 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	24/55 (44%)
CDX2	XP_011533177.1	Caudal_act	13..179	CDD:461413	46/206 (22%)
		Homeodomain	196..251	CDD:459649	24/54 (44%)