Protein Alignment CG18599 and CDX1

DIOPT Version :9

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001795.2
• Gene: CDX1 / 1044
• HGNCID: 1805
• Length: 265
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 49/183 - (26%)
• Similarity: 68/183 - (37%)
• Gaps: 58/183 - (31%)

  Fly   244 VAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSALQSLQQLHQQHHAQQQATLSFQREKLKSDS 308
            :.|.|.....|.|.|.|::....:|||..|....
Human   116 LGGPGTPSSPGAQRPTPYEWMRRSVAAGGGGGSG------------------------------- 149

  Fly   309 HKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRK 373
              |:..|:| .|.::|..|...||.||...:|:....:..||..|.|||.|||:||||||.|.||
Human   150 --KTRTKDK-YRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERK 211

  Fly   374 HHLELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHSVSTERTNGCSAASPSL 426
            .:.:..||:    :..|.|              .||.::      .:.|.|||
Human   212 VNKKKQQQQ----QPPQPP--------------MAHDIT------ATPAGPSL 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	24/51 (47%)
CDX1	NP_001795.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	9..153		11/69 (16%)
		Caudal_act	13..138	CDD:282574	6/21 (29%)
		Interaction with DNA. /evidence=ECO:0000305|PubMed:28473536	157..178		7/20 (35%)
		Homeobox	158..210	CDD:278475	24/51 (47%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000305|PubMed:28473536	196..207		8/10 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..265		13/58 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900