Protein Alignment CG18599 and en2

DIOPT Version :10

• Sequence 1: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_002932525.1
• Gene: en2 / 100498251
• XenbaseID: XB-GENE-853108
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 240
• Identity: 57/240 - (23%)
• Similarity: 89/240 - (37%)
• Gaps: 79/240 - (32%)

  Fly   203 DDNNKCYTSNPNNNNNNNNNG---GSNSGNNNSSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAG 264
            :.||:  ...|..:.:.:|.|   .:..||:.....:.||..|::.   |...|..:....||..
 Frog     5 EQNNR--EVEPQESGDESNRGILHQAPPGNHQPHHRITNFFIDNIL---RPEFGRRKEGISHQDE 64

  Fly   265 FAAVAAAVGAAPSALQSLQQLHQQHHAQQQA------TLSFQR-------EKLKSDSH------- 309
            ..:     |....||...:..|.:.:|.:.|      ||:..:       |.|||..|
 Frog    65 LFS-----GRDSGALSGAESAHHRANATEGAGGSKAITLTGDKKSDIAMEESLKSRGHNGDHSLS 124

  Fly   310 ------------------------------------------KKSAL----KNKRVRTIFTPEQL 328
                                                      ||:..    ::||.||.||.:||
 Frog   125 SDSDSSQASSKTSQQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKTTTTVTKEDKRPRTAFTADQL 189

  Fly   329 ECLEAEFERQQYMVGPERLYLAHTLKLTEAQVKVWFQNRRIKWRK 373
            :.|:|||:..:|:....|..||..|.|.|:|:|:||||:|.|.:|
 Frog   190 QRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	27/55 (49%)
en2	XP_002932525.1	Homeodomain	178..234	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	235..265	CDD:431338	57/240 (24%)