DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18599 and nkx6-2

DIOPT Version :9

Sequence 1:	NP_650701.1	Gene:	CG18599 / 42191	FlyBaseID:	FBgn0038592	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	XP_002937836.1	Gene:	nkx6-2 / 100038084	XenbaseID:	XB-GENE-484527	Length:	281	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	61/219 - (27%)
Similarity:	89/219 - (40%)	Gaps:	58/219 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 GSNSGNNNSSPSVNNFNCDSVAGNGRYLHGG--HQHPHPHQAGFAAVAAAVGAA----PSALQSL 282
            ||::...:|.|.:|..    ....|.|.:..  .::|.|       :|...|.|    |..:|..
Frog    78 GSSANLLSSLPRINGL----ATSTGMYFNPAAVSRYPKP-------LAELPGRAPIFWPGVMQGS 131

  Fly   283 QQLHQQHHAQQQATLSFQREKLKSDSHKKSALKNKRVRTIFTPEQLECLEAEFERQQYMVGPERL 347
            .....:.....||.:...::.           |.|..|..|:.:|:..||..||:.:|:.||||.
Frog   132 PWRDPRLGCPSQAGMVLDKDG-----------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERA 185

  Fly   348 YLAHTLKLTEAQVKVWFQNRRIKWRKHH-LELTQQRLALIRQTQLPGTSLLGNQVSVSANAAHSV 411
            .||::|.:||:||||||||||.||||.| .|:                        .:|...|..
Frog   186 RLAYSLGMTESQVKVWFQNRRTKWRKRHAAEM------------------------ATAKKKHDS 226

  Fly   412 STERTNGCSAASPSLQEEDNEDSK 435
            .||:..     ..|..|||:|.:|
Frog   227 ETEKMK-----ESSENEEDDEYNK 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18599	NP_650701.1	Homeobox	320..372	CDD:278475	28/51 (55%)
nkx6-2	XP_002937836.1	Homeobox	157..211	CDD:365835	29/53 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910