DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12320 and AT1G66510

DIOPT Version :9

Sequence 1:	NP_001303479.1	Gene:	CG12320 / 42189	FlyBaseID:	FBgn0038590	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_001323254.1	Gene:	AT1G66510 / 842969	AraportID:	AT1G66510	Length:	399	Species:	Arabidopsis thaliana

Alignment Length:	407	Identity:	111/407 - (27%)
Similarity:	199/407 - (48%)	Gaps:	54/407 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MDPQLALRLLADGGVLVIAGVPEGTEFGIDLCAYTIGPDFRGVKMIPPGVHYVWCSSRGPYG-DA 73
            ||.:.||.|:..|..|:...||:.|..|||...:.:||.|:|:||||||:|:|:.||....| :.
plant     1 MDSEKALELVKHGATLLFLDVPQYTLVGIDTQIFAVGPAFKGIKMIPPGIHFVFYSSSTRDGREF 65

  Fly    74 APRVGFVHFFHPNEIVVREWDHELEELRPRRIAEPEVERDRIRKNLAQLERVLAPYDYRYVVQWK 138
            :|.:||.....|::::||:|:.:.|.|  .:::|.|.||........:.::.|.||:.:...:|:
plant    66 SPTIGFFVDVAPSQVIVRKWNQQDEWL--TKVSEEEEERYSQAVRSLEFDKNLGPYNLKQYGEWR 128

  Fly   139 ELTGSVTESCVDRCRPTEGTIRTNIELQSCPDADRPRGGAAT---VSISRRNAAARILLDESELL 200
            .|:..:|:..|::..|..|.|....|....      :||..|   :::..:...::.....:|
plant   129 HLSNYITKDVVEKFEPVGGEITVTYESAIL------KGGPKTAMEIALDTQMKKSKFTTSSTE-- 185

  Fly   201 PDLKPVEGTAPRFTTVPLRVPQDALPA-DVSRHALDCIDAVDKLL--EGFETADGLIEELQLAYA 262
               :| :|....:|::|..:....:.. :::...||....::.:|  |..::.|.|:.|||.::.
plant   186 ---QP-KGNRFYYTSIPRIIKHKGMSGQELTSMNLDKTQLLESVLSKEYKDSEDLLLGELQFSFV 246

  Fly   263 FFLVGYSVESLAHWRKLLGLLAHSQTA--VTKHKLTYMKYSEVLAHQLPH-LPEELMVPGPHNTV 324
            .||:|.|:||...|:.::.||....:|  .|:.:| :.|:.:|:.|||.: |.:|  ..||...:
plant   247 AFLMGQSLESFMQWKSIVSLLLGCTSAPFQTRSQL-FTKFIKVIYHQLKYGLQKE--NSGPETGI 308

  Fly   325 Y------------------KDVRELL--VNLHAGGLSVSAERLTKRLEKKLGWEF------EGL- 362
            :                  ||...|:  .::..|.|.....:..:.||.:|||||      :|:
plant   309 HALLDDSWLASDSFLHFLCKDFFALVEETSVVDGDLLSWTRKFKELLENRLGWEFQKKSAVDGIY 373

  Fly   363 LDEDPEDQPVVIELPEA 379
            .:||.|..|||..|.|:
plant   374 FEEDDEYAPVVEMLDES 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12320	NP_001303479.1	AAR2	21..360	CDD:283049	97/374 (26%)
		Aar2_N	23..152	CDD:260099	42/129 (33%)
		Aar2_C	211..359	CDD:260100	42/173 (24%)
AT1G66510	NP_001323254.1	AAR2	12..364	CDD:368369	96/368 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	119	1.000	Domainoid score	I1918
eggNOG	1	0.900	-	-		E1_KOG3937
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9170
Inparanoid	1	1.050	133	1.000	Inparanoid score	I1860
OMA	1	1.010	-	-		QHG55834
OrthoDB	1	1.010	-	-		D1156337at2759
OrthoFinder	1	1.000	-	-		FOG0005859
OrthoInspector	1	1.000	-	-		oto3596
orthoMCL	1	0.900	-	-		OOG6_103436
Panther	1	1.100	-	-	LDO	PTHR12689
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5626
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840