DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12320 and Aar2

DIOPT Version :9

Sequence 1:	NP_001303479.1	Gene:	CG12320 / 42189	FlyBaseID:	FBgn0038590	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	XP_038960543.1	Gene:	Aar2 / 296312	RGDID:	1311066	Length:	420	Species:	Rattus norvegicus

Alignment Length:	410	Identity:	136/410 - (33%)
Similarity:	210/410 - (51%)	Gaps:	69/410 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SSMKMDPQLALRLLADGGVLVIAGVPEGTEFGIDLCAYTIGPDFRGVKMIPPGVHYVWCSS--RG 68
            :||:|||:||.:|..:|..:||..:|:|||||||..::.:||.||||||||||||:::.||  :.
  Rat    38 ASMQMDPELAKQLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGVHFLYYSSVDKA 102

  Fly    69 PYGDAAPRVGFVHFFHPNEIVVREWDHELEE--LRPRRIAEPEVERDRIRKNLAQLERVLAPYDY 131
            ...:..||:||.......|:.|..|:...||  |.|    .||.|.:.:|.||.:|::.|.||.|
  Rat   103 NPREVGPRMGFFLSLKQRELTVLRWNAVQEEVDLSP----APEAEVEAMRANLPELDQFLGPYPY 163

  Fly   132 RYVVQWKELTGSVTESCVDRCRP-------------------TEGTIRTNIELQSCPDADRPRGG 177
            ..:.:|..||..::|:.:::.:|                   |:..:..|:.|
  Rat   164 GTLKKWISLTNFISEATMEKLQPESRQICAFSDVLPVLSMRYTKDRVEQNLPL------------ 216

  Fly   178 AATVSISRRNAAARILLDESELLPDLKPVEGTAPRFTTVPLRV-PQDALPADVSRHALDCIDAVD 241
            ..|...|.:...||        ||::||..||..||:.:|.:: |..|.||:::||::|...|::
  Rat   217 CGTECRSYQEGLAR--------LPEMKPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALE 273

  Fly   242 KLL-EGFE-TADGLIEELQLAYAFFLVGYSVESLAHWRKLLGLLAHSQTAVTKHKLTYMKYSEVL 304
            .:| :.|. ....::.|||.|:..||:|...|:..||::||.||..|:||:.||...|:....:|
  Rat   274 TVLSKQFPGNPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSETAMVKHHALYVSLISIL 338

  Fly   305 AHQLPHLPEELMVPGPHNTVYKD--VRELLVNLHAGGLSVS--------AERLTKRLEKKLGWEF 359
            .|||..:|.:..|    :.|.:|  :...|....:...||:        ||:....|.||..|:|
  Rat   339 YHQLGEIPADFFV----DIVSQDNFLTSTLQVFFSSACSVAVEATLRKKAEKFQAHLTKKFRWDF 399

  Fly   360 EGLLDEDPED-QPVVIELPE 378
                ..:||| .|||:||||
  Rat   400 ----TSEPEDCAPVVVELPE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12320	NP_001303479.1	AAR2	21..360	CDD:283049	117/374 (31%)
		Aar2_N	23..152	CDD:260099	52/132 (39%)
		Aar2_C	211..359	CDD:260100	50/160 (31%)
Aar2	XP_038960543.1	AAR2	53..399	CDD:398787	117/373 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341364
Domainoid	1	1.000	170	1.000	Domainoid score	I3694
eggNOG	1	0.900	-	-		E1_KOG3937
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9170
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3727
OMA	1	1.010	-	-		QHG55834
OrthoDB	1	1.010	-	-		D1156337at2759
OrthoFinder	1	1.000	-	-		FOG0005859
OrthoInspector	1	1.000	-	-		oto97918
orthoMCL	1	0.900	-	-		OOG6_103436
Panther	1	1.100	-	-	LDO	PTHR12689
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5626
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770